Sensing small molecules with oligonucleotide aptamers.
Author(s) : CORINNE RAVELET, ERIC DAUSSE, ERIC PEYRIN, GUILLAUME DURAND, JEAN-JACQUES TOULME
Abstract
We developed biosensors in which the detection element is an oligonucleotide -an aptamer- obtained through a combinatorial process. We characterized aptamers specific for different biomarkers. They can be integrated into different devices, allowing their use either in a grafted format or in solution. We developped a multiplex assay signaling the presence of nucleoside derivatives by either surface plasmon resonance or fluorescence anisotropy.
No fo Author(s) : 5
Page(s) : 43 - 44
Electronic ISSN : A-F
Volume 2 :
Issue 1
Full Paper PDF
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