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International Journal of Advances in Computer Science and Its Applications

VEDEPSO Algorithm for Designing Unique Library of DNA Strands

Author(s) : KRISHNA VENI SELVAN, MOHD SAUFEE MUHAMMAD, SHARIFAH MASNIAH WAN MASRA

Abstract

Combinatorial optimization happens when there are two or more objectives to be optimized in solving a problem. The DNA words or oligonucleotides designing are one of a multiobjective combinatorial optimization problem. In this paper, the designations implied minimizations of H-measure, similarity, hairpin and continuity functions subjected to a predefine range of melting temperature and GC-content. A novel multi-swarm optimization approach is introduced to design a library of DNA strands. This approach is called vector evaluated differential evolution particle swarm optimization (VEDEPSO). The results obtained from the VEDEPSO algorithm is evaluated using Pareto dominance technique. A list of selected non-dominated solutions is shown as the final results from the research.

No fo Author(s) : 3
Page(s) : 18 - 21
Electronic ISSN : 2250 - 3765
Volume 4 : Issue 1
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